Cellular immunity in tuberculous pleural effusions: evidence of spontaneous lymphocyte proliferation and antigen-specific accelerated responses to purified protein derivative (PPD)
نویسندگان
چکیده
منابع مشابه
Purified Protein Derivative--PPD.
A 55-year-old physician had a PPD made as part of a clinical evaluation. Laboratory tests were unremarkable and PPD, read in 48 hours, showed an area of induration of 18 mm and an erythema of 51 mm (Panel A). A 2 mm punch biopsy was done in the center of the induration 96 hours after the injection. Histopathology showed an intense perivascular cuffing with macrophages and lymphocytes and edema ...
متن کاملAntimycobacterial antibodies in tuberculous pleural effusions: reliability of antigen 60.
1315 be generally advocated, however, it would be necessary to study larger groups of patients and controls to determine the sensitivity and specificity ofthe test. Ironically, the diagnostic ( ‘gold”) standard against which the test results would be weighed would be clinical evaluation with reproduction of symptoms with hyperventilation. In the final analysis, therefore, I believe that the dia...
متن کاملAntimycobacterial Antibodies in Tuberculous Pleural Effusions: Reliability of Antigen 60
1315 be generally advocated, however, it would be necessary to study larger groups of patients and controls to determine the sensitivity and specificity ofthe test. Ironically, the diagnostic ( ‘gold”) standard against which the test results would be weighed would be clinical evaluation with reproduction of symptoms with hyperventilation. In the final analysis, therefore, I believe that the dia...
متن کامل[Tuberculous pleural effusions].
Tuberculous pleural effusion is a common manifestation of the primary form of the disease or consequence of the reactivation of a latent infection due to the M. tuberculosis. Advances in the laboratory methods have contributed to better diagnose and understand the pathophysiology of the effusion secondary to tuberculosis. However, although a predominant lymphocytic pleural effusion is suspiciou...
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Mycobacterium tuberculosis remains a pathogen of con¬ siderable clinical and public health importance. Clas¬ sically, tuberculous pleuritis was regarded as a disease ofyoung adults characterized by a unilateral, lymphocytic exudate with a self-limited short-term course. In the last two decades, how¬ ever, there has been increasing recognition that tuberculous pleuritis is occurring in an older ...
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ژورنال
عنوان ژورنال: Clinical & Experimental Immunology
سال: 2008
ISSN: 0009-9104
DOI: 10.1111/j.1365-2249.1992.tb07931.x